Members

2022 Summer

2017 Summer

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Professor Thomas J. Meade

tmeade@northwestern.edu

 

Principle Investigator

 - Postdoctoral Fellow CalTech 1988-1990

 - NIH Fellow Harvard Medical School 1985-1987

 - Ph.D.: The Ohio State University 1985 

Postdoctoral researchers 

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Jian-Hong Tang

jian-hong.tang@northwestern.edu

 - Ph.D. Institute of Chemistry, Chinese Academy of Sciences, 2018

The aspects of my research interests are designing, synthesizing, and utilizing new molecular systems for bioimaging and therapeutic applications.  In particular, we are interested in developing enzyme-activatable molecular MRI and FL probes for real-time tracking gene therapy and tumor imaging.  

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Matt Bailey

Matthew.bailey@northwestern.edu

- Ph.D. Wayne State University 2021

- B.S. Grand Valley State University, 2014

I’m a synthetic chemist with special interests in physical and analytical chemistry. My main projects in the Meade lab involve synthesizing custom self-assembled monolayers on gold nanoparticles and gold electrode surfaces for biological theranostics and electrochemical sensing, respectively. I have an extensive background in magnetic resonance imaging, the design of small-molecule contrast agents, and chemical photocatalysis.

I'm cute looking and have a can-do attitude!

Graduate students

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Andrew Johnson

andrewjohnson2015@u.northwestern.edu 

 - B.A. Chemistry, Central College, 2015

My research involves the use of nanoparticles as a delivery method for MR contrast agents and Cobalt Schiff base complexes. Currently, I am developing targeted nanoconstructs  that can deliver MR contrast agents to tumor cells in a receptor expression dependent manner.

National Science Foundation (NSF) Graduate Research Fellowship Honorable Mention, 2016
Alumnae Grant, 2018

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Christopher Brue

w9s4z6@u.northwestern.edu 

 - B.S. Chemistry and History, The Ohio State University, 2015

My research involves the development and characterization of cobalt-schiff base complexes to be used as potential therapeutics for Altzheimer’s Disease.

Graduate Teaching Fellow 2018-2019

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Shaunna McLeod

shaunnamcleod2015@u.northwestern.edu 

 - B.S. Chemistry and B.A. Mathematics, State University of New York at Buffalo,    2015

My research focuses on improving the sensitivity of Gd(III) MRI contrast agents for molecular imaging applications through two approaches. The first strategy reduces the background signal of activatable agents by modulating the electronic relaxation time (T1e) of Gd(III), accomplished through magnetic coupling interactions. The second strategy utilizes carbon nanodiamonds as a platform for nanoconaugate contrast agents. 

National Science Foundation (NSF) Graduate Research Fellowship, 2017
Teaching Certificate Program 2017-2018
Graduate Teaching Fellow 2018-2019

ACS Women Chemists Committee Eli Lilly Travel Award, 2020

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Megan Kaster

megankaster2022@u.northwestern.edu 

 - B.S. Chemistry (Summa Cum Laude), Oakland University, 2017

My research interests are focused on the development of lanthanide-based MR-shift probes. In addition, I am developing bioactivated nanoparticle MR imaging constructs with gold and carbon nanoparticles.

Chemistry of Life Processes Institute Pre-Doctoral Fellowship, 2018

Ruth L. Kirschstein National Research Service Award (NRSA F31), 2018

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Meghan Dukes

meghanward2022@u.northwestern.edu 

 - B.S. (Suma Cum Laude) Chemistry, Auburn University, 2017

My research focuses on synthetic medications to our family of Co(III)-Schiff base transcription factor inhibitors to generate a platform synthon.

Ruth L. Kirschstein National Research Service Award (NRSA F31), 2018

National Science Foundation (NSF) Graduate Research Fellowship Honorable Mention, 2019

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Casey Adams

CaseyAdams2022@u.northwestern.edu 

 - B.A. (Summa Cum Laude), College of the Holy Cross, 2017

I am interested in the development of bioactivated MR contrast agents. I am currently working on a calcium activated contrast agent for non-invasive neuronal imaging.

Ruth L. Kirschstein National Research Service Award (NRSA F31), 2018

Joseph Lambert Award, 2019

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Hao Li

haoli2022@u.northwestern.edu

- M.S. Chemistry, University of Illinois, Urbana-Champaign, 2016

- B.S. Chemistry (Magna Cum Laude), University of California, Irvine, 2014

The goal of my main project is to develop dual activatable MR and fluorescent probes that will enable the sensitive and selective detection of biomarkers in vivo via dual modality imaging. This approach synergistically combines the deep-tissue penetration of MRI and the high sensitivity of fluorescence imaging. 

Alumnae Grant, 2019

Alumnae Grant, 2020

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Hendryck Gellineau

hendryck.gellineau@northwestern.edu

- B.A. Chemistry (Magna Cum Laude), Cornell University, 2019

 

My work focuses on utilizing cobalt Schiff base complexes as novel antibiotics by exploiting their axial ligand exchange chemistry.

 

Medical Scientist Training Program, 2027

Patrick G. and Shirley W. Ryan Fellowship for Nanotechnology, 2021-2023

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Minrui Luo

MinruiLuo2021@u.northwestern.edu

 - B. S. Chemistry and B. A. Physics, Syracuse University, 2020

My project focuses on developing a theragnostic targeting tool for molecular MR imaging of alkaline phosphatase in liver cancer by attaching targeted ligands and contrast agents to gold nanoparticles for improved liver cancer tissue visualization and discrimination.

 

Chemistry of Life Processes Institute Pre-Doctoral Fellowship, 2022

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Andrew Brotherton

AndrewBrotherton2027@u.northwestern.edu

 - B.S. Chemistry (Summa Cum Laude) University of North Carolina at Charlotte, 2022

I have a background in push-pull fluorophores for sensing and photocatalytic applications and am currently working on reagentless redox active self-assembled monolayers for biosensor applications. 

National Science Foundations (NSF) Graduate Research Fellowship, 2022

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Naedum DomNwachukwu 

Naedum.domnwachukwu@northwestern.edu

 - B.S. Biomedical Engineering (Cum Laude) Cornell University, 2020

My research background is in biomaterials and drug delivery systems. In the Meade Lab, I work on developing novel diagnostic tools such as high relaxivity and bioresponsive MR contrast agents and self-assembled monolayers for electrochemical biosensors.

Medical Scientist Training Program, 2028

Undergraduate researchers 

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Sami Zaidi

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Caroline Roach