Selected Publications
From 2015 to present:
1H Parashift Probes for Ratiometric Detection of Nitroreductase
Kaster M. A., Caldwell M. A., Roach C. M., Bailey, M. D., Meade, T. J.
ACS Inorganic Chemistry, 2025, In press
Gadolinium Conjugated Lipoic-Acid Hydrogels for Magnetic Resonance Imaging
Brotherton, A. R., Phillips-Sorich, B., DomNwachukwu, N., Bailey, M. D., Patel, A. S., Parigi, G., Luchinat, C., Meade, T. J.
ACS Applied Bio Materials, 2025, DOI: 10.1021/acsabm.5c00584
Ultra-high resolution magnetic resonance microscopy of in situ gadolinium gold nanoparticles labeled cells in the rat brain
Kisel, A.; Luo, M.; Bailey, M. D.; Ghuman, H.; Rotz, M.; Campos, V.; Vieira, M.; Hitchens, K. T.; Meade, T. J.; Modo, M. M.
Chemical Science, 2025, DOI:10.1039/d5sc01588j
MRI detection of senescent cells in porcine knee joints with a β-galactosidase responsive Gd-chelate
Nernekli, K., Mangarova, D.B., Daldrup-Link, H. E., Meade, T. J.
npj Imaging, 2025, 3, 18
Luo, M., Bailey, M. D., Hyun, K., Lei, Y., Meade, T. J.
ACS Applied Materials & Interfaces, 2025, 17, 19, 28000–28011
Gli pathway-targeted Co(III) Schiff base complexes inhibit migration of basal cell carcinoma cells
Bond, C. E., Olson, K. D., Punar, M., Friedman, L. B., Tang, J. H., Luo, M., Bailey, M. D., Holmgren, R. A., Meade, T. J.
RSC Advances, 2025, 15, 8572-8579
Brotherton, A. R., DomNwachukwu, N., Bailey, M. D., Rivnay, J., Meade, T. J.
Langmuir, 2025, 41, 12, 8144–8151
MR Imaging Reveals Dynamic Aggregation of Multivalent Glycoconjugates in Aqueous Solution
Tang, J.-H., Luo, M., Tsao, W., Waters, E. A., Parigi, G., Luchinat, C., Meade, T. J.
Inorganic Chemistry, 2024, 63, 24662-24671
Synthesis and Relaxivity of Gadolinium-Based DOTAGA Conjugated 3-Phosphoglycerate
Brotherton, A. R., Mohamed S. N., Meade, T. J.
Dalton Transactions, 2024, 53, 17777 - 17782
HaloTag-Modified, Ferrocene Labeled Self-Assembled Monolayers for Protein Sensing
Brotherton, A. R., Neupane, G. P., Ji, X., Sullivan, K., Bailey, M. D., Berns, E. J., Rivnay, J., Mrksich, M., Meade, T. J.
Langmuir, 2024, 40, 22856-22864.
Mitrut, R. E., Stranford, D. M., DiBiase, B. N., Chan, J. M., Bailey, M. D., Luo, M., Harper, C. S., Meade, T. J., Wang, M., Leonard, J. N.
J Extracell Vesicles. 2024 Jul; 13(7): e12469-.
Development of Ln(III) Derivatives as 19F Parashift Probes
Kaster, M. A., Caldwell, M. A., Meade, T. J..
Inorganic Chemistry 2024, 63, 21, 9877–9887.
Musculoskeletal imaging of senescence
Daldrup-Link, H.E., Suryadevara, V., Tanyildizi, Y., Nernekli, K., Tang, J. -H., Meade, T. J..
Skeletal Radiology V53, 1879–1887, (2024)
Molecular Engineering of Self-Immolative Bioresponsive MR Probes
Tang, J.-H.; Li, H.; Yuan, C.; Parigi, G.; Luchinat, C.; Meade, T. J..
Journal of the American Chemical Society 2023, 145, 10045-10050.
Engineered Non-Viral Protein Cages Modified for MR Imaging
Kaster, M.; Levasseur, M.; Edwardson, T.; Caldwell, M.; Hofmann, D.; Licciardi, G.; Parigi, G.; Luchinat, C.; Hilvert, D.; Meade, TJ.
ACS Applied Bio Materials, 2023, 6, 2, 591–602.
Molecular Bio-Sensors and the Role of Metal Ions
Edited by Meade, TJ.
ISBN 9781032135786
Published September 27, 2022 by CRC Press.
Dukes, M.; Modo, M.; Meade, TJ.
CRC Press, 2022; pp 261-286.
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Dukes, M.; Meade, TJ.
Biomedicines, 2022, 10, 2376.
Delivery of Targeted Co(III)-DNA Inhibitors of Gli Proteins to Disrupt Hedgehog Signaling
Dukes, M.; Bajema, E.; Whittemore, T.; Holmgren, R.; Meade, TJ.
Bioconjugate Chem., 2022, 33, 643–653.
Functional Disruption of Gli1-DNA Recognition via a Cobalt(III) Complex
Brue, C.; Dukes, M.; Masotti, M.; Holmgren, R.; Meade, TJ.
ChemMedChem, 2022, 17, e2022000.
Li, H., Lou, D., Yuan, C., Wang, X., Wang, J., Basilion, JB., Meade, TJ.
J. Am. Chem. Soc., 2021, 143, 41, 17097-17108 .
Real-Time Tracking of AAV Gene Therapy with Enzyme Activated MR Probes
Taghian, T., Esteves, MG.,Edwards, HG., Meade, TJ.
Molecular Therapy, 2021, 29, 124-134.
Towards Imaging Pt Chemoresistance Using Gd(III)-Pt(II Theranostic MR Contrast Agents
Adams, CJ., Meade, TJ.
ChemMedChem, 2021, 16, 1-10.
Imaging Bacteria with Contrast-Enhanced MR
Adams, CJ., Meade, TJ.
Met Ions Life Sci (A. Sigel, E. Freisinger and R. Sigel, eds.), 2021. Chapter 15, 425-435.
Magnetic Resonance Theranostics: An Overview of Gadolinium(III)-based Strategies and Magnetic Particle Imaging.
McLeod, SM., Meade, TJ.
Met Ions Life Sci (A. Sigel, E. Freisinger and R. Sigel, eds.), 2021, Chapter 12, 347-370.
Cobalt(III) Schiff Base complexes stabilize non-fibrillar amyloid-β aggregates with reduced toxicity
Roberts, KF., Brue, CR., Preston, A., Baxter, D., Herzog, E., Varelas, E., Meade, TJ.
J. Inorg. Biochem. 2020, 213, 111265-111275.
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Targeted Radiosensitizers for MR-Guided Radiation Therapy of Prostate Cancer
Luo, D.; Johnson, A.; Wang, X.; Li, H.; Erokwu, B. O.; Springer, S.; Lou, J.; Ramamurthy, G.;
Flask, C. A.; Burda, C.; Burda, C.; Basilion, J.; and Meade TJ.
Nano Lett. 2020, 20, 7159-7167.
Maximizing Magnetic Resonance Contrast in Gd(III) Nanoconjugates: Investigation of Proton
Relaxation in Zirconium Metal–Organic Frameworks
Mcleod, SM., Robison, L., Parigi, G., Olszewski, A., Drout, RJ., Gong, X., Islamoglu, T.,
Luchinat, C., Farha, OK., and Meade, TJ.
ACS Appl. Mater. Interfaces. 2020, 12, 41157-41166.
Advances in optical and electrochemical techniques for biomedical imaging
Long, YT., Meade, TJ.
Chem. Sci. 2020,11, 6940-6941
A Ln(III)-3-hydroxypyridine pH responsive probe optimized by DFT
Caldwell, MA., Brue, CR., Whittemore, TJ., Meade, TJ.
RSC Adv 2020, 10, 8994-8999.
Gd(III)-Pt(IV) theranostic contrast agents for tandem MR imaging and chemotherapy
Adams, CJ., and Meade, TJ.
Chem. Sci. 2020, 11, 2524 - 2530
A Multimodal Ca(II) Responsive Near IR-MR Contrast Agent Exhibiting High Cellular Uptake.
Adams, CJ., Krueger, R., and Meade, TJ.
ACS Chem. Biol. 2020, 15, 334-341.
Laura M. Lilley, Sarah Kamper, Michael Caldwell, Zer Keen Chia, David Ballweg, Luke Vistain, Jeffrey Krimmel,
Teresa Anne Mills, Keith MacRenaris, Paul Lee Emily, Alexandria Waters, Thomas J. Meade
Angew Chem Int Ed Engl 2019, 132, 396-402.
Cobalt-Schiff base complexes: preclinical research and potential therapeutic uses.
Bajema, EA, Roberts,KF, Meade TJ.
Met Ions Life Sci (A. Sigel, E. Freisinger and R. Sigel, eds.),
Guest Editor Peggy L. Carver,
Vol. 19., Chapter 11, 2019, 268-301.
Molecular Magnetic Resonance Imaging with Gd(III)-Based Contrast Agents: Challenges and Key Advances
Hao Li and Thomas J. Meade
J Am Chem Soc 2019, 43, 17025-17041.
A water-soluble nanoconjugate for enhanced cellular delivery of receptor-targeted MR contrast agents
Laura K. Moore, Michael Caldwell, Taryn R Townsend, Keith W MacRenaris, Georgette MoyleHeyrman, Nikhil Rammohan,
Erika K Schonher, Joanna E. Burdette, Dean Ho, and Thomas J. Meade
Bioconjug Chem 2019, 30, 2947-2957 .
Bimodal Fluorescence-Magnetic Resonance Contrast Agent for Apoptosis Imaging
Li, H.; Parigi, G.; Luchinat, C.; Meade, T. J.
J Am Chem Soc 2019, 15, 6224-6233.
Aysenur Iscen, Christopher R. Brue, Kaleigh F. Roberts, Joy Kim,
George C. Schatz, and Thomas J. Meade
J Am Chem Soc 2019, 42, 16685-16695.
Rotz, M. W.; Holbrook, R. J.; MacRenaris, K. W.; Meade, T. J.
Bioconjug Chem 2018, 29, 3544-3549.
Synthesis and evaluation of MR probes for targeted-reporter imaging.
Verma, K. D.; Massing, J. O.; Kamper, S. G.; Carney, C. E.;
MacRenaris, K. W.; Basilion, J. P.; Meade, T. J.
Chem Sci 2017, 8, 5764-5768.
Lilley, L. M.; Du, K.; Krzyaniak, M. D.; Parigi, G.; Luchinat, C.; Harris, T. D.; Meade, T. J.
Inorg Chem 2018, 57, 5810-5819.
Phase engineering and optical properties of 2D MoSe2: Promise and pitfalls
Eve D. Hanson, Laura M. Lilley, Jeffrey D. Cain, Shiqiang Hao, Edgar Palacios, Koray Aydin,
Chris Wolverton, Thomas Meade, Vinayak P. Dravid
Materials Chemistry and Physics 2019, 225, 219-226.
Preslar, A. T.; Lilley, L. M.; Sato, K.; Zhang, S.; Chia, Z. K.; Stupp, S. I.; Meade, T. J.
ACS Appl Mater Interfaces 2017, 9, 39890-39894.
Injectable biomimetic liquid crystalline scaffolds enhance muscle stem cell transplantation.
Sleep, E.; Cosgrove, B. D.; McClendon, M. T.; Preslar, A. T.; Chen, C. H.; Sangji, M. H.;
Perez, C. M. R.; Haynes, R. D.; Meade, T. J.; Blau, H. M.; Stupp, S. I.
Proc Natl Acad Sci U S A 2017, 114, E7919-E7928.
Magnetic barcode imaging for contrast agents.
Hung, A. H.; Lilley, L. M.; Hu, F.; Harrison, V. S.; Meade, T. J.
Magn Reson Med 2017, 77, 970-978.
Gd(III)-Gold Nanoconjugates Provide Remarkable Cell Labeling for High Field
Rammohan, N.; Holbrook, R. J.; Rotz, M. W.; MacRenaris, K. W.; Preslar, A. T.;
Carney, C. E.; Reichova, V.; Meade, T. J.
Bioconjug Chem 2017, 28, 153-160.
Preslar, A. T.; Tantakitti, F.; Park, K.; Zhang, S.; Stupp, S. I.; Meade, T. J.
ACS Nano 2016, 10, 7376-84.
Shape-Dependent Relaxivity of Nanoparticle-Based T1 Magnetic Resonance Imaging Contrast Agents.
Culver, K. S.; Shin, Y. J.; Rotz, M. W.; Meade, T. J.; Hersam, M. C.; Odom, T. W.
J Phys Chem C Nanomater Interfaces 2016, 120, 22103-22109.
Nanodiamond-Gadolinium(III) Aggregates for Tracking Cancer Growth In Vivo at High Field.
Rammohan, N.; MacRenaris, K. W.; Moore, L. K.; Parigi, G.; Mastarone, D. J.; Manus, L. M.;
Lilley, L. M.; Preslar, A. T.; Waters, E. A.; Filicko, A.; Luchinat, C.; Ho, D.; Meade, T. J.
Nano Lett 2016, 16, 7551-7564.
Gd(III)-Dithiolane Gold Nanoparticles for T1-Weighted Magnetic Resonance Imaging of the Pancreas.
Holbrook, R. J.; Rammohan, N.; Rotz, M. W.; MacRenaris, K. W.; Preslar, A. T.; Meade, T. J.
Nano Lett 2016, 16, 3202–3209.
Cell-Permeable Esterase-Activated Ca(II)-Sensitive MRI Contrast Agent.
MacRenaris, K. W.; Ma, Z.; Krueger, R. L.; Carney, C. E.; Meade, T. J.
Bioconjug Chem 2016, 27, 465-73.
DNA-gadolinium-gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells.
Nicholls, F. J.; Rotz, M. W.; Ghuman, H.; MacRenaris, K. W.; Meade, T. J.; Modo, M.
Biomaterials 2016, 77, 291-306.
Vistain, L. F.; Yamamoto, N.; Rathore, R.; Cha, P.; Meade, T. J.
Chembiochem 2015, 16, 2065-72.
Tuning cobalt(III) Schiff base complexes as activated protein inhibitors.
Heffern, M. C.; Reichova, V.; Coomes, J. L.; Harney, A. S.; Bajema, E. A.; Meade, T. J.
Inorg Chem 2015, 54, 9066-74.
Targeted Inhibition of Snail Activity in Breast Cancer Cells by Using a Co(III) -Ebox Conjugate.
Vistain, L. F.; Yamamoto, N.; Rathore, R.; Cha, P.; Meade, T. J.
Chembiochem 2015, 16, 2065-72.
Water-soluble lipophilic MR contrast agents for cell membrane labeling.
Carney, C. E.; MacRenaris, K. W.; Meade, T. J.
J Biol Inorg Chem 2015, 20, 971-7.
Banerjee, S. R.; Ngen, E. J.; Rotz, M. W.; Kakkad, S.; Lisok, A.; Pracitto, R.; Pullambhatla, M.;
Chen, Z.; Shah, T.; Artemov, D.; Meade, T. J.; Bhujwalla, Z. M.; Pomper, M. G.
Angew Chem Int Ed Engl 2015, 54, 10778-82.
Multimeric Near IR-MR Contrast Agent for Multimodal In Vivo Imaging.
Harrison, V. S.; Carney, C. E.; MacRenaris, K. W.; Waters, E. A.; Meade, T. J.
J Am Chem Soc 2015, 137, 9108-16.
Theranostic Magnetic Nanostructures (MNS) for Cancer.
Nandwana, V.; De, M.; Chu, S.; Jaiswal, M.; Rotz, M.; Meade, T. J.; Dravid, V. P.
Cancer Treat Res 2015, 166, 51-83.
Nanodiscs as a Modular Platform for Multimodal MR-Optical Imaging.
Carney, C. E.; Lenov, I. L.; Baker, C. J.; MacRenaris, K. W.; Eckermann, A. L.;
Sligar, S. G.; Meade, T. J.,
Bioconjug Chem 2015, 26, 899-905.
High relaxivity Gd(III)-DNA gold nanostars: investigation of shape effects on proton relaxation.
Rotz, M. W.; Culver, K. S.; Parigi, G.; MacRenaris, K. W.; Luchinat, C.;
Odom, T. W.; Meade, T. J.
ACS Nano 2015, 9, 3385-96.
Holbrook, R. J.; Weinberg, D. J.; Peterson, M. D.; Weiss, E. A.; Meade, T. J.
J Am Chem Soc 2015, 137, 3379-85.
