Real-Time Tracking of AAV Gene Therapy with Enzyme Activated MR Probes

Taghian, T., Esteves, MG.,Edwards, HG., Meade, TJ.

Molecular Therapy, 2021, 29, 124-134.

Towards Imaging Pt Chemoresistance Using Gd(III)-Pt(II Theranostic MR Contrast Agents

Adams, CJ., Meade, TJ.

ChemMedChem, 2021, 16, 1-10.

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Imaging Bacteria with Contrast-Enhanced MR

Adams, CJ., Meade, TJ. 

Met Ions Life Sci (A. Sigel, E. Freisinger and R. Sigel, eds.), 2021. Chapter 15, 425-435.

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Magnetic Resonance Theranostics: An Overview of Gadolinium(III)-based Strategies and Magnetic Particle Imaging.

McLeod, SM., Meade, TJ. 

Met Ions Life Sci (A. Sigel, E. Freisinger and R. Sigel, eds.), 2021, Chapter  12, 347-370.

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Cobalt(III) Schiff Base complexes stabilize non-fibrillar amyloid-β aggregates with reduced toxicity

Roberts, KF., Brue, CR., Preston, A., Baxter, D., Herzog, E., Varelas, E., Meade, TJ.

J. Inorg. Biochem. 2020, 213, 111265-111275.

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Targeted Radiosensitizers for MR-Guided Radiation Therapy of Prostate Cancer

Dong Luo, Andrew Johnson, Xinning Wang, Hao Li, Bernadette O Erokwu,

Sarah Springer, Jason Lou,Gopalakrishnan Ramamurthy, Chris A. Flask,

Clemens Burda, James P. Basilion and Thomas J. Meade

Nano Lett.  2020, 20, 7159-7167.

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Maximizing Magnetic Resonance Contrast in Gd(III) Nanoconjugates: Investigation of Proton

Relaxation in Zirconium Metal–Organic Frameworks

Shaunna M McLeod, Lee Robison, Giacomo Parigi, Alyssa Olszewski, Riki J Drout,
Xinyi Gong, Timur Islamoglu, Claudio Luchinat, Omar K. Farha, and Thomas J. Meade

ACS Appl. Mater. Interfaces. 2020, 12, 41157-41166.

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Advances in optical and electrochemical techniques for biomedical imaging

Long, YT., Meade, TJ. 

Chem. Sci. 2020,11, 6940-6941

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A Ln(III)-3-hydroxypyridine pH responsive probe optimized by DFT

Caldwell, MA., Brue, CR., Whittemore, TJ., Meade, TJ.

RSC Adv 2020, 10, 8994-8999.

Gd(III)-Pt(IV) theranostic contrast agents for tandem MR imaging and chemotherapy

Casey J Adams,Thomas J. Meade

Chem. Sci.  2020, 11, 2524 - 2530

A Multimodal Ca(II) Responsive Near IR-MR Contrast Agent Exhibiting High Cellular Uptake.

Casey J Adams, Ruby Krueger, Thomas J. Meade

ACS Chem. Biol. 2020, 15, 334-341.

Self‐Immolative Activation of β‐Galactosidase‐Responsive Probes for In Vivo MR Imaging in Mouse Models

Laura M. Lilley, Sarah Kamper, Michael Caldwell, Zer Keen Chia, David Ballweg, Luke Vistain, Jeffrey Krimmel,

Teresa Anne Mills,  Keith MacRenaris, Paul Lee  Emily, Alexandria Waters, Thomas J. Meade

Angew Chem Int Ed Engl 2019, 132, 396-402.

Molecular Magnetic Resonance Imaging with Gd(III)-Based Contrast Agents: Challenges and Key Advances

Hao Li and Thomas J. Meade

J Am Chem Soc  2019, 43, 17025-17041.

Bimodal Fluorescence-Magnetic Resonance Contrast Agent for Apoptosis Imaging

Li, H.; Parigi, G.; Luchinat, C.; Meade, T. J.

J Am Chem Soc 2019, 15, 6224-6233.

A Markedly Improved Synthetic Approach for the Preparation of Multifunctional Au-DNA Nanoparticle Conjugates Modified with Optical and MR Imaging Probes.

Rotz, M. W.; Holbrook, R. J.; MacRenaris, K. W.; Meade, T. J.

Bioconjug Chem 2018, 29, 3544-3549.

Synthesis and evaluation of MR probes for targeted-reporter imaging.

Verma, K. D.; Massing, J. O.; Kamper, S. G.; Carney, C. E.;

MacRenaris, K. W.; Basilion, J. P.; Meade, T. J.

Chem Sci 2017, 8, 5764-5768.

Effect of Magnetic Coupling on Water Proton Relaxivity in a Series of Transition Metal Gd(III) Complexes.

Lilley, L. M.; Du, K.; Krzyaniak, M. D.; Parigi, G.; Luchinat, C.; Harris, T. D.; Meade, T. J.

Inorg Chem 2018, 57, 5810-5819.

Phase engineering and optical properties of 2D MoSe2: Promise and pitfalls

Eve D. Hanson, Laura M. Lilley, Jeffrey D. Cain, Shiqiang Hao, Edgar Palacios, Koray Aydin,

Chris Wolverton, Thomas Meade, Vinayak P. Dravid

Materials Chemistry and Physics 2019, 225, 219-226.

Calcium-Induced Morphological Transitions in Peptide Amphiphiles Detected by 19F-Magnetic Resonance Imaging.

Preslar, A. T.; Lilley, L. M.; Sato, K.; Zhang, S.; Chia, Z. K.; Stupp, S. I.; Meade, T. J.

ACS Appl Mater Interfaces 2017, 9, 39890-39894.

Injectable biomimetic liquid crystalline scaffolds enhance muscle stem cell transplantation.

Sleep, E.; Cosgrove, B. D.; McClendon, M. T.; Preslar, A. T.; Chen, C. H.; Sangji, M. H.;

Perez, C. M. R.; Haynes, R. D.; Meade, T. J.; Blau, H. M.; Stupp, S. I.

Proc Natl Acad Sci U S A  2017, 114, E7919-E7928.

Magnetic barcode imaging for contrast agents.

Hung, A. H.; Lilley, L. M.; Hu, F.; Harrison, V. S.; Meade, T. J.

Magn Reson Med 2017, 77, 970-978.

Gd(III)-Gold Nanoconjugates Provide Remarkable Cell Labeling for High Field

Magnetic Resonance Imaging.

Rammohan, N.; Holbrook, R. J.; Rotz, M. W.; MacRenaris, K. W.; Preslar, A. T.;

Carney, C. E.; Reichova, V.; Meade, T. J.

Bioconjug Chem 2017, 28, 153-160.

19F Magnetic Resonance Imaging Signals from Peptide Amphiphile Nanostructures Are Strongly Affected by Their Shape.

Preslar, A. T.; Tantakitti, F.; Park, K.; Zhang, S.; Stupp, S. I.; Meade, T. J.

ACS Nano 2016, 10, 7376-84.

Shape-Dependent Relaxivity of Nanoparticle-Based T1 Magnetic Resonance Imaging Contrast Agents.

Culver, K. S.; Shin, Y. J.; Rotz, M. W.; Meade, T. J.; Hersam, M. C.; Odom, T. W.

J Phys Chem C Nanomater Interfaces 2016, 120, 22103-22109.

Nanodiamond-Gadolinium(III) Aggregates for Tracking Cancer Growth In Vivo at High Field.

Rammohan, N.; MacRenaris, K. W.; Moore, L. K.; Parigi, G.; Mastarone, D. J.; Manus, L. M.;

Lilley, L. M.; Preslar, A. T.; Waters, E. A.; Filicko, A.; Luchinat, C.; Ho, D.; Meade, T. J.

Nano Lett 2016, 16, 7551-7564.

Gd(III)-Dithiolane Gold Nanoparticles for T1-Weighted Magnetic Resonance Imaging of the Pancreas.

Holbrook, R. J.; Rammohan, N.; Rotz, M. W.; MacRenaris, K. W.; Preslar, A. T.; Meade, T. J.

Nano Lett  2016, 16, 3202–3209.

Cell-Permeable Esterase-Activated Ca(II)-Sensitive MRI Contrast Agent.

MacRenaris, K. W.; Ma, Z.; Krueger, R. L.; Carney, C. E.; Meade, T. J.

Bioconjug Chem 2016, 27, 465-73.

DNA-gadolinium-gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells.

Nicholls, F. J.; Rotz, M. W.; Ghuman, H.; MacRenaris, K. W.; Meade, T. J.; Modo, M.

Biomaterials 2016, 77, 291-306.

Targeted delivery of gold nanoparticle contrast agents for reporting gene detection by magnetic resonance imaging.

Vistain, L. F.; Yamamoto, N.; Rathore, R.; Cha, P.; Meade, T. J.

Chembiochem 2015, 16, 2065-72.

Tuning cobalt(III) Schiff base complexes as activated protein inhibitors.

Heffern, M. C.; Reichova, V.; Coomes, J. L.; Harney, A. S.; Bajema, E. A.; Meade, T. J.

Inorg Chem 2015, 54, 9066-74.

Targeted Inhibition of Snail Activity in Breast Cancer Cells by Using a Co(III) -Ebox Conjugate.

Vistain, L. F.; Yamamoto, N.; Rathore, R.; Cha, P.; Meade, T. J.

Chembiochem 2015, 16, 2065-72.

Water-soluble lipophilic MR contrast agents for cell membrane labeling.

Carney, C. E.; MacRenaris, K. W.; Meade, T. J.

J Biol Inorg Chem 2015, 20, 971-7.

Synthesis and Evaluation of Gd(III) -Based Magnetic Resonance Contrast Agents for Molecular Imaging of Prostate-Specific Membrane Antigen.

Banerjee, S. R.; Ngen, E. J.; Rotz, M. W.; Kakkad, S.; Lisok, A.; Pracitto, R.; Pullambhatla, M.;

Chen, Z.; Shah, T.; Artemov, D.; Meade, T. J.; Bhujwalla, Z. M.; Pomper, M. G.

Angew Chem Int Ed Engl 2015, 54, 10778-82.

Multimeric Near IR-MR Contrast Agent for Multimodal In Vivo Imaging.

Harrison, V. S.; Carney, C. E.; MacRenaris, K. W.; Waters, E. A.; Meade, T. J.

J Am Chem Soc 2015, 137, 9108-16.

Theranostic Magnetic Nanostructures (MNS) for Cancer.

Nandwana, V.; De, M.; Chu, S.; Jaiswal, M.; Rotz, M.; Meade, T. J.; Dravid, V. P.

Cancer Treat Res 2015, 166, 51-83.

Nanodiscs as a Modular Platform for Multimodal MR-Optical Imaging.

Carney, C. E.; Lenov, I. L.; Baker, C. J.; MacRenaris, K. W.; Eckermann, A. L.;

Sligar, S. G.; Meade, T. J.,

Bioconjug Chem 2015, 26, 899-905.

High relaxivity Gd(III)-DNA gold nanostars: investigation of shape effects on proton relaxation.

Rotz, M. W.; Culver, K. S.; Parigi, G.; MacRenaris, K. W.; Luchinat, C.;

Odom, T. W.; Meade, T. J.

ACS Nano 2015, 9, 3385-96.

Light-activated protein inhibition through photoinduced electron transfer of a ruthenium(II)-cobalt(III) bimetallic complex.

Holbrook, R. J.; Weinberg, D. J.; Peterson, M. D.; Weiss, E. A.; Meade, T. J.

J Am Chem Soc 2015, 137, 3379-85.

Modulation of amyloid-β aggregation by histidine-coordinating Cobalt(III) Schiff base complexes.

Heffern, M. C.; Velasco, P. T.; Matosziuk, L. M.; Coomes, J. L.; Karras, C.;

Ratner, M. A.; Klein, W. L.; Eckermann, A. L.; Meade, T. J.

Chembiochem 2014, 15, 1584-9.

Graphene oxide enhances cellular delivery of hydrophilic small molecules by co-incubation.

Hung, A. H.; Holbrook, R. J.; Rotz, M. W.; Glasscock, C. J.; Mansukhani, N. D.;

MacRenaris, K. W.; Manus, L. M.; Duch, M. C.; Dam, K. T.; Hersam, M. C.; Meade, T. J.

ACS Nano 2014, 8, 10168-77

A multimeric MR-optical contrast agent for multimodal imaging.

Harrison, V. S.; Carney, C. E.; Macrenaris, K. W.; Meade, T. J.

Chem Commun (Camb) 2014, 50, 11469-71.

Gd(III)-labeled peptide nanofibers for reporting on biomaterial localization in vivo.

Preslar, A. T.; Parigi, G.; McClendon, M. T.; Sefick, S. S.; Moyer, T. J.; Haney, C. R.;

Waters, E. A.; MacRenaris, K. W.; Luchinat, C.; Stupp, S. I.; Meade, T. J.

ACS Nano 2014, 8, 7325-32.

Cell labeling via membrane-anchored lipophilic MR contrast agents.

Carney, C. E.; MacRenaris, K. W.; Mastarone, D. J.; Kasjanski, D. R.; Hung, A. H.; Meade, T. J.

Bioconjug Chem 2014, 25, 945-54

Synthesis and characterization of a porphyrazine-Gd(III) MRI contrast agent

and in vivo imaging of a breast cancer xenograft model.

Trivedi, E. R.; Ma, Z.; Waters, E. A.; Macrenaris, K. W.; Subramanian, R.;

Barrett, A. G.; Meade, T. J.; Hoffman, B. M.

Contrast Media Mol Imaging 2014, 9, 313-22.

Progesterone-targeted magnetic resonance imaging probes.

Townsend, T. R.; Moyle-Heyrman, G.; Sukerkar, P. A.; MacRenaris, K. W.;

Burdette, J. E.; Meade, T. J.

Bioconjug Chem 2014, 25, 1428-37.

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pH-Responsive Theranostic Polymer-Caged Nanobins (PCNs): Enhanced Cytotoxicity and T1 MRI Contrast by Her2-Targeting.

Hong, B. J.; Swindell, E. P.; Macrenaris, K. W.; Hankins, P. L.; Chipre, A. J.;

Mastarone, D. J.; Ahn, R. W.; Meade, T. J.; O'Halloran, T. V.; Nguyen, S. T.

Part Part Syst Charact 2013, 30, 770-774.

Lanthanide probes for bioresponsive imaging.

Heffern, M. C.; Matosziuk, L. M.; Meade, T. J.

Chem Rev 2014, 114, 4496-539.

Mechanisms of Gadographene-Mediated Proton Spin Relaxation.

Hung, A. H.; Duch, M. C.; Parigi, G.; Rotz, M. W.; Manus, L. M.; Mastarone, D. J.; Dam, K. T.;

Gits, C. C.; Macrenaris, K. W.; Luchinat, C.; Hersam, M. C.; Meade, T. J.

J Phys Chem C Nanomater Interfaces 2013, 117.

High dynamic range processing for magnetic resonance imaging.

Hung, A. H.; Liang, T.; Sukerkar, P. A.; Meade, T. J.

PLoS One 2013, 8, e77883.

Spectroscopic elucidation of the inhibitory mechanism of Cys2His2 zinc finger transcription factors

by cobalt(III) Schiff base complexes.

Heffern, M. C.; Kurutz, J. W.; Meade, T. J.

Chemistry 2013, 19, 17043-53.

Preface for the forum on metals in medicine and health: new opportunities and approaches to improving health.

Crans, D. C.; Meade, T. J.

Inorg Chem 2013, 52, 12181-3.

Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma.

Jensen, S. A.; Day, E. S.; Ko, C. H.; Hurley, L. A.; Luciano, J. P.; Kouri, F. M.; Merkel, T. J.;

Luthi, A. J.; Patel, P. C.; Cutler, J. I.; Daniel, W. L.; Scott, A. W.; Rotz, M. W.; Meade, T. J.;

Giljohann, D. A.; Mirkin, C. A.; Stegh, A. H.

Sci Transl Med 2013, 5, 209ra152.